SCHEMBL14007758

SCHEMBL14007758

Nc1cc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)cc1[N+](=O)[O-]

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
USP2 O75604 3/20 0.68
L3MBTL1 Q9Y468 1/20 0.68
MEN1 O00255 2/20 0.63
POLB P06746 2/20 0.63
KMT2A Q03164 2/20 0.63
ALPL P05186 1/20 0.63
ALPI P09923 1/20 0.63
ALPG P10696 1/20 0.63
CA9 Q16790 16/20 0.54
CA1 P00915 14/20 0.54
CA2 P00918 14/20 0.54
ATM Q13315 1/20 0.53
PLEC Q15149 1/20 0.53
DNASE1L3 Q13609 1/20 0.52
PRMT1 Q99873 1/20 0.52
CA12 O43570 6/20 0.50
CA14 Q9ULX7 2/20 0.49
CA7 P43166 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25829608 0.88 USP2 (0.80) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL14007759 0.84 USP2 (0.49) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL20254033 0.82 USP2 (0.77) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL14007766 0.82 USP2 (0.47) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL3481432 0.81 USP2 (1.00) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL30023431 0.81 USP2 (1.00) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL13384808 0.81 USP2 (0.85) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL14640188 0.80 USP2 (0.74) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL14007760 0.80 USP2 (0.45) USP2L3MBTL1MEN1POLBKMT2A
SCHEMBL13052173 0.79 MEN1 (0.65) USP2L3MBTL1MEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080281104-A1 Membrane-Anchoring Fluorescent Probe THE UNIVERSITY OF TOKYO (JP) 2008-11-13 US disclosed
US-20080281104-A1 Membrane-Anchoring Fluorescent Probe THE UNIVERSITY OF TOKYO (JP) 2008-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080281104-A1 Membrane-Anchoring Fluorescent Probe MBOAT1, MBOAT7, APMAP USP2 3837/4885L3MBTL1 1417/4885MEN1 1788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.