SCHEMBL14008166

SCHEMBL14008166

CCCCCCCCCCNC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 10/20 0.66
CASP2 P42575 1/20 0.53
ZDHHC20 Q5W0Z9 1/20 0.50
ZDHHC2 Q9UIJ5 1/20 0.50
NAAA Q02083 1/20 0.50
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
PRCP P42785 1/20 0.47
FAAH O00519 2/20 0.47
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
GNAI3 P08754 1/20 0.45
GNAO1 P09471 1/20 0.45
GNAI1 P63096 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22472041 1.00 EPHX1 (0.66) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL14008172 1.00 EPHX1 (0.66) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL11698967 0.98 EPHX1 (0.62) EPHX1CASP2ZDHHC20ZDHHC2NAAA
SCHEMBL4433251 0.91 EPHX1 (0.53) EPHX1CASP2ALDH1A1POLBSMN1; SMN2
SCHEMBL13660345 0.89 MEN1 (0.58) EPHX1MEN1KMT2AALDH1A1POLB
SCHEMBL13660344 0.89 MEN1 (0.58) EPHX1MEN1KMT2AALDH1A1POLB
SCHEMBL13660337 0.89 MEN1 (0.58) EPHX1MEN1KMT2AALDH1A1POLB
SCHEMBL2797759 0.82 MMP1 (0.43) EPHX1MEN1KMT2AALDH1A1POLB
SCHEMBL14008176 0.81 EPHX1 (0.49) EPHX1ALDH1A1SMN1; SMN2
SCHEMBL24376776 0.81 EPHX1 (0.68) EPHX1CASP2ZDHHC20ZDHHC2NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
US-20080160445-A1 Planographic printing plate material, and method of preparing planographic printing plate employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-03 US disclosed
US-20080131812-A1 Resin for printing plate material and lithographic printing plate material by use thereof KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-06-05 US disclosed
US-7285375-B2 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-10-23 US disclosed
US-7273692-B2 Planographic printing plate material and planographic printing plate preparing process KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-09-25 US disclosed
US-20070020555-A1 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-25 US disclosed