SCHEMBL14008199

SCHEMBL14008199

CCC(COCCCNC(=O)C(C)(C)NC(=O)C(Cl)(Cl)Cl)(COCCCNC(=O)C(C)(C)NC(=O)C(Cl)(Cl)Cl)COCCCNC(=O)C(C)(C)NC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.36
THRB P10828 1/20 0.35
HPGD P15428 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HTT P42858 1/20 0.33
TSHR P16473 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
LMNA P02545 1/20 0.31
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14008197 0.89 THRB (0.41) EPHX1THRBHPGDMEN1KMT2A
SCHEMBL13432090 0.86 HPGD (0.36) EPHX1THRBHPGDMEN1KMT2A
SCHEMBL16325477 0.85 EPHX1 (0.41) EPHX1THRBTSHRSMN1; SMN2ALDH1A1
SCHEMBL13432084 0.77 THRB (0.41) EPHX1THRBHPGDMEN1KMT2A
SCHEMBL16316536 0.73 TSHR (0.43) EPHX1THRBHPGDHTTTSHR
SCHEMBL16315601 0.73 TSHR (0.43) EPHX1THRBHPGDHTTTSHR
SCHEMBL14008165 0.73 TSHR (0.47) EPHX1HPGDKMT2AHTTTSHR
SCHEMBL20752404 0.71 FAAH (0.44) THRBHPGDMEN1KMT2ATSHR
SCHEMBL14008176 0.71 EPHX1 (0.49) EPHX1HPGDTSHRSMN1; SMN2ALDH1A1
SCHEMBL14040381 0.71 HPGD (0.36) EPHX1THRBHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
US-20080160445-A1 Planographic printing plate material, and method of preparing planographic printing plate employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-03 US disclosed
US-20080131812-A1 Resin for printing plate material and lithographic printing plate material by use thereof KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-06-05 US disclosed
US-20080131812-A1 Resin for printing plate material and lithographic printing plate material by use thereof KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-06-05 US disclosed
US-7285375-B2 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-10-23 US disclosed
US-7273692-B2 Planographic printing plate material and planographic printing plate preparing process KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-09-25 US disclosed
US-20070020555-A1 Photosensitive composition, photosensitive lithography plate and method for producing lithography plate KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-25 US disclosed