Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.31 |
| ▸ | HTR2C | P28335 | 5/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68525 | 0.83 | PTGER1 (0.33) | PTGER1PTGER4PTGER3PTGER2MMP9 | |
| SCHEMBL1400849 | 0.83 | PPARG (0.37) | PTGER1PTGER4PTGER3PTGER2PDK2 | |
| SCHEMBL5198183 | 0.83 | RXRA (0.41) | PTGER1PTGER4PTGER3PTGER2S1PR1 | |
| SCHEMBL5198621 | 0.81 | KDM4E (0.43) | PPARD | |
| SCHEMBL1400796 | 0.80 | PDK2 (0.32) | PDK2HTR2CSLC6A4PPARDHTR2A | |
| SCHEMBL1400797 | 0.80 | PDK2 (0.32) | PDK2HTR2CSLC6A4PPARDHTR2A | |
| SCHEMBL2843431 | 0.70 | HTR2C (0.43) | HTR2CSLC6A4 | |
| SCHEMBL67070 | 0.69 | RXRA (0.44) | S1PR1S1PR3S1PR5FFAR4 | |
| SCHEMBL4968634 | 0.67 | AKR1C3 (0.49) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL4968622 | 0.67 | AKR1C3 (0.49) | PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814871-B1 | COMPOUNDS THAT MODULATE PPARY TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2011-03-02 | — | — | EP | disclosed |