Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 5/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986509 | 0.75 | ALOX5 (0.46) | ALOX5PARP10SMOMAPK14 | |
| SCHEMBL3002712 | 0.73 | PARP10 (0.48) | PARP10HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2986838 | 0.73 | MAP4K3 (0.37) | ALOX5HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL13248437 | 0.73 | MAP4K3 (0.37) | ALOX5HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2989774 | 0.71 | PARP10 (0.50) | ALOX5PARP10HPGDSMOMAPK14 | |
| SCHEMBL14642258 | 0.70 | PARP10 (0.51) | PARP10HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2246968 | 0.70 | NPC1 (0.41) | ALOX5PARP10HPGDSMN1; SMN2MAOB | |
| SCHEMBL12356701 | 0.70 | PARP10 (0.55) | PARP10HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2250280 | 0.70 | PARP10 (0.55) | PARP10HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL2251349 | 0.69 | PARP10 (0.57) | ALOX5PARP10HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156721-A1 | DIPHENYL SUBSTITUTED ALKANES | MERCK & CO., INC. (US) | 2008-12-24 | — | — | WO | disclosed |