Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.46 |
| ▸ | SMO | Q99835 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986509 | 0.93 | ALOX5 (0.46) | PARP10ALOX5MAPK14SMODRD4 | |
| SCHEMBL3000605 | 0.89 | DRD4 (0.49) | DRD4SLC6A5 | |
| SCHEMBL3000342 | 0.89 | HPGDS (0.53) | DRD4SLC6A5 | |
| SCHEMBL2995598 | 0.89 | USP30 (0.47) | DRD4MEN1KMT2A | |
| SCHEMBL3000230 | 0.89 | SLC6A5 (0.58) | DRD4SLC6A5 | |
| SCHEMBL2986740 | 0.87 | PARP10 (0.57) | PARP10MAPK14SMOHPGDHSD17B10 | |
| SCHEMBL3000321 | 0.86 | ALOX5AP (0.52) | PARP10MAPK14SMODRD4HPGD | |
| SCHEMBL2993276 | 0.85 | PARP10 (0.52) | PARP10ALOX5MAPK14SMODRD4 | |
| SCHEMBL2997269 | 0.84 | ALOX5 (0.52) | PARP10ALOX5MAPK14SMODRD4 | |
| SCHEMBL2993319 | 0.84 | CHRNA7 (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2546232-A1 | Diphenyl Substituted Alkanes | Merck Sharp & Dohme Corp. (US) | 2013-01-16 | — | — | EP | disclosed |
| US-20100190761-A1 | DIPHENYL SUBSTITUTED ALKANES | MERCK SHARP & DOHME CORP. | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190761-A1 | DIPHENYL SUBSTITUTED ALKANES | ALOX5, ALOX15, ALOX15B | PARP10 1048/4885ALOX5 1/4885MAPK14 2199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.