Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 7/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13803984 | 0.89 | DHFR (0.62) | DHFR | |
| SCHEMBL14417306 | 0.89 | DHFR (0.73) | DHFR | |
| SCHEMBL24192873 | 0.89 | DHFR (0.73) | DHFR | |
| SCHEMBL17011394 | 0.87 | DHFR (0.75) | DHFR | |
| SCHEMBL29578377 | 0.87 | DHFR (0.75) | DHFR | |
| SCHEMBL24343655 | 0.86 | DHFR (0.71) | DHFR | |
| SCHEMBL24343680 | 0.85 | DHFR (0.68) | DHFR | |
| SCHEMBL20286623 | 0.85 | DHFR (0.72) | DHFR | |
| SCHEMBL3176848 | 0.84 | DHFR (0.73) | DHFR | |
| SCHEMBL13530096 | 0.84 | DHFR (0.73) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452901-B2 | Anti-cancer phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-11-18 | — | — | US | disclosed |
| US-7432261-B2 | Anti-inflammatory phosphonate compounds | GILEAD SCIENCES, INC. (US) | 2008-10-07 | — | — | US | disclosed |