Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 7/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417306 | 1.00 | DHFR (0.73) | DHFR | |
| SCHEMBL17011394 | 0.95 | DHFR (0.75) | DHFR | |
| SCHEMBL29578377 | 0.95 | DHFR (0.75) | DHFR | |
| SCHEMBL24343655 | 0.91 | DHFR (0.71) | DHFR | |
| SCHEMBL24343680 | 0.91 | DHFR (0.68) | DHFR | |
| SCHEMBL24193095 | 0.90 | DHFR (0.69) | DHFR | |
| SCHEMBL26422283 | 0.90 | DHFR (0.73) | DHFR | |
| Aminopterin SCHEMBL1626034 | 0.89 | DHFR (0.76) | DHFR | |
| Aminopterin SCHEMBL20769794 | 0.89 | DHFR (0.76) | DHFR | |
| Aminopterin SCHEMBL29443569 | 0.89 | DHFR (0.76) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126297-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2023-07-06 | — | — | WO | disclosed |
| WO-2022008419-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2022-01-13 | — | — | WO | disclosed |