Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19828775 | 0.87 | CYP2C19 (0.42) | GAAKDM4EKMT2AMEN1CYP2C9 | |
| SCHEMBL14340622 | 0.84 | ALDH1A1 (0.40) | GAAALDH1A1 | |
| SCHEMBL6036515 | 0.82 | SMN1; SMN2 (0.55) | GAA | |
| SCHEMBL9029829 | 0.79 | MKNK1 (0.38) | GAAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL14010048 | 0.77 | MKNK1 (0.38) | GAALMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL12719407 | 0.76 | BCHE (0.49) | GAAKMT2ACYP3A4 | |
| SCHEMBL25810430 | 0.75 | ALDH1A1 (0.45) | GAALMNAKMT2AALDH1A1MAPT | |
| SCHEMBL13346513 | 0.74 | GAA (0.68) | GAAKDM4ELMNAKMT2AMEN1 | |
| SCHEMBL12021613 | 0.73 | KDM4E (0.55) | GAAKDM4ELMNAALDH1A1CYP3A4 | |
| SCHEMBL8351923 | 0.72 | HTT (0.41) | GAALMNAALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449462-B2 | Triazole derivatives which inhibit vasopressin antagonistic activity | PFIZER, INC. (US) | 2008-11-11 | — | — | US | disclosed |
| US-20070203132-A1 | Triazole derivatives which inhibit vasopressin antagonistic activity | PFIZER INC | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203132-A1 | Triazole derivatives which inhibit vasopressin antagonistic activity | AVPR2, PRLHR, AVPR1A | GAA 4659/4885KDM4E 4040/4885LMNA 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.