Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761339 | 0.83 | ALDH1A1 (0.45) | MKNK1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL12065915 | 0.82 | — | — | |
| SCHEMBL9029829 | 0.82 | MKNK1 (0.38) | MKNK1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL22078923 | 0.78 | HDAC8 (0.54) | MKNK1PKMALDH1A1MEN1KMT2A | |
| SCHEMBL2446419 | 0.78 | — | — | |
| SCHEMBL6036515 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2GAACARM1PRMT6 | |
| SCHEMBL14010055 | 0.77 | GAA (0.39) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL13045996 | 0.77 | BCHE (0.43) | PKMALDH1A1SMN1; SMN2GAAHTT | |
| SCHEMBL25810430 | 0.77 | ALDH1A1 (0.45) | MKNK1ALDH1A1KMT2ASMN1; SMN2GAA | |
| SCHEMBL4056944 | 0.77 | MKNK1 (0.39) | MKNK1PKMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449462-B2 | Triazole derivatives which inhibit vasopressin antagonistic activity | PFIZER, INC. (US) | 2008-11-11 | — | — | US | disclosed |
| US-20070203132-A1 | Triazole derivatives which inhibit vasopressin antagonistic activity | PFIZER INC | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203132-A1 | Triazole derivatives which inhibit vasopressin antagonistic activity | AVPR2, PRLHR, AVPR1A | MKNK1 1806/4885PKM 760/4885ALDH1A1 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.