Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 7/20 | 0.42 |
| ▸ | INPP5A | Q14642 | 4/20 | 0.42 |
| ▸ | INPP5B | P32019 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14010073 | 0.81 | PTPN1 (0.48) | KDM4EALDH1A1HPGDHSD17B10PTPN1 | |
| SCHEMBL14873906 | 0.72 | INPPL1 (0.42) | INPPL1INPP5AINPP5BKDM4EUSP2 | |
| SCHEMBL28046741 | 0.71 | PLK1 (0.46) | INPPL1INPP5AINPP5BHTR2AHTR2C | |
| SCHEMBL29429257 | 0.70 | MAPT (0.67) | INPPL1INPP5AINPP5BKDM4EUSP2 | |
| SCHEMBL759513 | 0.70 | MAPT (0.67) | INPPL1INPP5AINPP5BKDM4EUSP2 | |
| SCHEMBL1100136 | 0.69 | INPPL1 (0.57) | INPPL1INPP5AINPP5BKDM4EUSP2 | |
| Phosphoric Acid SCHEMBL27473336 | 0.69 | MAPT (0.65) | INPPL1INPP5AINPP5BKDM4EUSP2 | |
| SCHEMBL31555373 | 0.69 | INPPL1 (0.57) | INPPL1INPP5AINPP5BKDM4EUSP2 | |
| O-Xylene SCHEMBL29031713 | 0.68 | INPPL1 (0.55) | INPPL1INPP5AINPP5BKDM4EUSP2 | |
| SCHEMBL29199066 | 0.68 | INPPL1 (0.55) | INPPL1INPP5AINPP5BKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287396-A1 | Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections | TARGANTA THERAPEUTICA INC. (CA) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287396-A1 | Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections | BPGM, PSPH, PGLS | INPPL1 78/4885INPP5A 43/4885INPP5B 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.