Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12151567 | 0.87 | ALDH1A1 (0.42) | ALDH1A1HPGDL3MBTL1KMT2AMEN1 | |
| SCHEMBL13530757 | 0.87 | ALDH1A1 (0.42) | ALDH1A1HPGDL3MBTL1KMT2AMEN1 | |
| SCHEMBL4244870 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDKMT2ATSHRTDP1 | |
| SCHEMBL11519883 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDKMT2ATSHRTDP1 | |
| SCHEMBL14356276 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDKMT2ATSHRTDP1 | |
| SCHEMBL12556315 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDKMT2ATSHRTDP1 | |
| SCHEMBL14565297 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDKMT2ATSHRTDP1 | |
| SCHEMBL7850077 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDKMT2ATSHRTDP1 | |
| SCHEMBL13672341 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDKMT2ATSHRTDP1 | |
| SCHEMBL16684307 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDKMT2ATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7452901-B2 | Anti-cancer phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-11-18 | — | — | US | disclosed |
| US-7452901-B2 | Anti-cancer phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2008-11-18 | — | — | US | disclosed |