Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | PPM1B | O75688 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14356276 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPK1POLBGAA | |
| SCHEMBL11519883 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPK1POLBGAA | |
| SCHEMBL16684307 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPK1POLBGAA | |
| SCHEMBL13010080 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPK1POLBGAA | |
| SCHEMBL13672341 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPK1POLBGAA | |
| SCHEMBL14565297 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPK1POLBGAA | |
| SCHEMBL12556315 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPK1POLBGAA | |
| SCHEMBL7850077 | 1.00 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPK1POLBGAA | |
| SCHEMBL22915735 | 0.86 | ALDH1A1 (0.59) | ALDH1A1HPGDMAPK1POLBGAA | |
| SCHEMBL14580144 | 0.84 | ALDH1A1 (0.57) | ALDH1A1HPGDMAPK1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897759-B2 | Metabolically stable puromycin analogs | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2011-03-01 | — | — | US | disclosed |
| US-20090069556-A1 | METABOLICALLY STABLE PUROMYCIN ANALOGS | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069556-A1 | METABOLICALLY STABLE PUROMYCIN ANALOGS | PDF, NPEPPS, RNMT | ALDH1A1 2124/4885HPGD 1896/4885MAPK1 1819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.