Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.34 |
| ▸ | BCHE | P06276 | 6/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1400890 | 0.83 | EPHX2 (0.36) | RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL68438 | 0.81 | ESR1 (0.35) | ACHEBCHERAB9AMAPTSMN1; SMN2 | |
| SCHEMBL68783 | 0.71 | AOC3 (0.41) | ACHEBCHERAB9AKMT2A | |
| SCHEMBL67519 | 0.71 | EPHX2 (0.42) | ALDH1A1KMT2A | |
| SCHEMBL1749744 | 0.70 | ITGB3 (0.39) | FAAH | |
| SCHEMBL1749745 | 0.70 | ITGB3 (0.39) | FAAH | |
| SCHEMBL68003 | 0.69 | EPHX2 (0.33) | ACHEBCHERAB9AMAPTSMN1; SMN2 | |
| SCHEMBL68004 | 0.69 | EPHX2 (0.33) | ACHEBCHERAB9AMAPTSMN1; SMN2 | |
| SCHEMBL1401230 | 0.69 | ACHE (0.37) | ACHEBCHERAB9AMAPTSMN1; SMN2 | |
| SCHEMBL68745 | 0.69 | FFAR1 (0.42) | MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814871-B1 | COMPOUNDS THAT MODULATE PPARY TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2011-03-02 | — | — | EP | claimed |