Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902239 | 0.90 | PTGDR2 (0.40) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL2763295 | 0.83 | PTGDR2 (0.49) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL4641968 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL1034563 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDKMT2AGAAMEN1 | |
| SCHEMBL4642180 | 0.80 | ALDH1A1 (0.57) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL2762658 | 0.80 | PTGDR2 (0.49) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL4646850 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL4647759 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL554848 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL1200995 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293781-A1 | Salicylic Acid Derivatives | NICOX S.A. (FR) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293781-A1 | Salicylic Acid Derivatives | PTGS2, PTGS1, PTGES2 | ALDH1A1 51/4885HPGD 27/4885HTT 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.