Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.51 |
| ▸ | PPARA | Q07869 | 17/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5014125 | 0.94 | PPARG (0.58) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL5023628 | 0.93 | PPARA (0.50) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL14010682 | 0.89 | PPARG (0.56) | PPARGPPARAPPARD | |
| SCHEMBL5015073 | 0.84 | PPARG (0.67) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL5015518 | 0.84 | PPARG (0.67) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL5017679 | 0.84 | PPARG (0.67) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL5015601 | 0.83 | PPARG (0.57) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL5015608 | 0.83 | PPARA (0.57) | PPARGPPARAPPARDPGRADORA3 | |
| SCHEMBL5015569 | 0.81 | PPARA (0.55) | PPARGPPARAPPARD | |
| SCHEMBL5023583 | 0.81 | PPARA (0.49) | PPARGPPARAPPARDPGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456293-B2 | Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use | SK HOLDING CO., LTD (KR) | 2008-11-25 | — | — | US | disclosed |