SCHEMBL5015569

SCHEMBL5015569

CCOC(=O)C(Cc1ccc(OCCn2c(C(F)(F)F)nc3ccccc32)cc1)OCC

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 13/20 0.55
PPARG P37231 12/20 0.55
PPARD Q03181 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5015070 0.93 PPARA (0.54) PPARAPPARGPPARD
SCHEMBL5015518 0.92 PPARG (0.67) PPARAPPARGPPARD
SCHEMBL5017679 0.92 PPARG (0.67) PPARAPPARGPPARD
SCHEMBL5015073 0.92 PPARG (0.67) PPARAPPARGPPARD
SCHEMBL14010682 0.92 PPARG (0.56) PPARAPPARGPPARD
SCHEMBL5023628 0.89 PPARA (0.50) PPARAPPARGPPARD
SCHEMBL5023583 0.89 PPARA (0.49) PPARAPPARGPPARD
SCHEMBL5015105 0.88 PPARA (0.58) PPARAPPARGPPARD
SCHEMBL5484833 0.85 SMN1; SMN2 (0.49) PPARAPPARGPPARD
SCHEMBL5488110 0.85 SMN1; SMN2 (0.49) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7456293-B2 Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use SK HOLDING CO., LTD (KR) 2008-11-25 US disclosed
US-7456293-B2 Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use SK HOLDING CO., LTD (KR) 2008-11-25 US disclosed
US-7456293-B2 Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use SK HOLDING CO., LTD (KR) 2008-11-25 US disclosed
US-20060281802-A1 Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use SK BIOPHARMACEUTICALS CO., LTD. (KR) 2006-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060281802-A1 Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use SLC5A1, CPT1A, GPR119 PPARA 174/4885PPARG 166/4885PPARD 196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.