Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.56 |
| ▸ | PPARA | Q07869 | 10/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5017679 | 0.93 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5015073 | 0.93 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5015518 | 0.93 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL5015569 | 0.92 | PPARA (0.55) | PPARGPPARAPPARD | |
| SCHEMBL14010685 | 0.89 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL5488110 | 0.86 | SMN1; SMN2 (0.49) | PPARGPPARAPPARDMAPT | |
| SCHEMBL5484833 | 0.86 | SMN1; SMN2 (0.49) | PPARGPPARAPPARDMAPT | |
| SCHEMBL5015605 | 0.86 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL5015070 | 0.85 | PPARA (0.54) | PPARGPPARAPPARD | |
| SCHEMBL5023587 | 0.85 | PPARG (0.50) | PPARGPPARAPPARDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456293-B2 | Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use | SK HOLDING CO., LTD (KR) | 2008-11-25 | — | — | US | disclosed |