Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854361 | 1.00 | KDM1A (0.44) | KDM1AMAOAMAOBMEN1KMT2A | |
| SCHEMBL4854356 | 1.00 | KDM1A (0.44) | KDM1AMAOAMAOBMEN1KMT2A | |
| SCHEMBL14010982 | 0.84 | SIGMAR1 (0.46) | KDM1AMAOA | |
| SCHEMBL4855649 | 0.84 | SIGMAR1 (0.46) | KDM1AMAOA | |
| SCHEMBL4855655 | 0.84 | SIGMAR1 (0.46) | KDM1AMAOA | |
| SCHEMBL6678390 | 0.78 | IDO1 (0.39) | ALDH1A1HTT | |
| SCHEMBL4859955 | 0.78 | IDO1 (0.39) | ALDH1A1HTT | |
| SCHEMBL27621129 | 0.75 | EDNRA (0.44) | MAOAMEN1KMT2ANPC1HPGD | |
| SCHEMBL14074344 | 0.73 | CYP3A4 (0.39) | MEN1KMT2AHPGDALDH1A1RAB9A | |
| SCHEMBL4862964 | 0.73 | CYP3A4 (0.39) | MEN1KMT2AHPGDALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300271-A1 | Novel compounds and a novel process for their preparation | FAGNOU KEITH | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300271-A1 | Novel compounds and a novel process for their preparation | NUDT1, NCL, NUCB2 | KDM1A 4826/4885MAOA 1639/4885MAOB 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.