Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.32 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.32 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998198 | 0.86 | ALDH1A1 (0.67) | ALDH1A1TSHRGLAKDM4ECYP3A4 | |
| SCHEMBL25225894 | 0.86 | ALDH1A1 (0.67) | ALDH1A1TSHRGLAKDM4ECYP3A4 | |
| SCHEMBL25271744 | 0.86 | ALDH1A1 (0.67) | ALDH1A1TSHRGLAKDM4ECYP3A4 | |
| SCHEMBL13998185 | 0.85 | ALDH1A1 (0.66) | ALDH1A1TSHRGLAKDM4ECYP3A4 | |
| Harpagoside SCHEMBL893387 | 0.82 | ALDH1A1 (1.00) | ALDH1A1TSHRGLAKDM4ECYP3A4 | |
| SCHEMBL23720483 | 0.81 | ALDH1A1 (0.71) | ALDH1A1TSHRGLAKDM4ECYP3A4 | |
| SCHEMBL24278467 | 0.81 | ALDH1A1 (0.71) | ALDH1A1TSHRGLAKDM4ECYP3A4 | |
| SCHEMBL6847752 | 0.81 | ALDH1A1 (0.88) | ALDH1A1TSHRGLAKDM4ECYP3A4 | |
| SCHEMBL29425763 | 0.71 | ALDH1A1 (0.80) | ALDH1A1TSHRGLAKDM4ECYP3A4 | |
| SCHEMBL14137980 | 0.67 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP2C19POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080319042-A1 | Compositions and methods for treatment of liver disease | CALECO PHARMA CORP. | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319042-A1 | Compositions and methods for treatment of liver disease | HCCS, HAVCR2, PYGL | ALDH1A1 1067/4885TSHR 4396/4885GLA 1048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.