Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5054663 | 0.89 | ALDH1A1 (0.56) | MAPTKDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL5054851 | 0.88 | MAPT (0.59) | MAPTKDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL14012192 | 0.86 | MAPT (0.51) | MAPTKDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL27368087 | 0.84 | KDM4E (0.58) | MAPTKDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL14012188 | 0.84 | MAPT (0.60) | MAPTKDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL5051380 | 0.80 | MAPT (0.47) | MAPTKDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL22281315 | 0.79 | KDM4E (0.68) | MAPTKDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL15226797 | 0.76 | KDM4E (0.58) | MAPTKDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL87136 | 0.75 | KDM4E (0.62) | MAPTKDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL5575131 | 0.74 | KDM4E (0.47) | MAPTKDM4ESMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293153-A1 | Photolabile System with Instantaneous Fluorescence Reporting Function | COLORADO SEMINARY, WHICH OWNS AND OPERATES THE UNIVERSITY OF DENVER | 2008-11-27 | — | — | US | disclosed |