Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 11/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401593 | 0.92 | F2 (0.50) | OPRD1CAPN1CTSBF2MMP9 | |
| SCHEMBL1401188 | 0.91 | OPRD1 (0.44) | OPRD1CAPN1CTSBF2MMP9 | |
| SCHEMBL1401284 | 0.88 | HSD17B10 (0.47) | CAPN1F2MMP9MMP8GHSR | |
| SCHEMBL1401582 | 0.86 | F2 (0.48) | OPRD1F2TACR1CYP51A1 | |
| SCHEMBL1401107 | 0.85 | TACR1 (0.42) | F2TACR1 | |
| SCHEMBL1401110 | 0.85 | TACR1 (0.42) | F2TACR1 | |
| SCHEMBL3392487 | 0.84 | F2 (0.45) | CAPN1F2MMP9MMP8TACR1 | |
| SCHEMBL1401075 | 0.83 | TACR1 (0.47) | TACR1 | |
| SCHEMBL1401262 | 0.82 | F10 (0.43) | CAPN1TACR1GHSR | |
| SCHEMBL3361699 | 0.81 | CYP51A1 (0.46) | OPRD1F2CYP51A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100824-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2011-03-02 | — | — | EP | claimed |