Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | UGCG | Q16739 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 2/20 | 0.42 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 2/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | PROC | P04070 | 1/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401593 | 0.89 | F2 (0.50) | MMP9MMP8GHSRCAPN1F2 | |
| SCHEMBL1401188 | 0.88 | OPRD1 (0.44) | MMP9MMP8GHSRPLGPLAU | |
| SCHEMBL1401268 | 0.88 | OPRD1 (0.48) | MMP9MMP8GHSRCAPN1F2 | |
| SCHEMBL3392487 | 0.84 | F2 (0.45) | MMP9MMP8GHSRPLGF10 | |
| SCHEMBL1401582 | 0.83 | F2 (0.48) | F2 | |
| SCHEMBL6320694 | 0.83 | MMP9 (0.56) | MMP9MMP8GHSRFCER2MME | |
| SCHEMBL24435894 | 0.83 | FPR2 (0.47) | HSD17B10CHRM1 | |
| SCHEMBL3267073 | 0.83 | MMP9 (0.41) | MMP9MMP8GHSRFCER2CAPN1 | |
| SCHEMBL1401107 | 0.82 | TACR1 (0.42) | PLAUF10F2 | |
| SCHEMBL1401110 | 0.82 | TACR1 (0.42) | PLAUF10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100824-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2011-03-02 | — | — | EP | claimed |