Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.73 |
| ▸ | MEN1 | O00255 | 7/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.73 |
| ▸ | USP2 | O75604 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.73 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | FGB | P02675 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.61 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998834 | 0.91 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| 1,4-Dimethoxyanthraquinone SCHEMBL3417221 | 0.86 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL31495885 | 0.81 | MAPT (0.58) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29494862 | 0.79 | MAPT (0.79) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5105540 | 0.79 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9846513 | 0.79 | MAPT (0.79) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6901121 | 0.77 | MAPT (0.81) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL612831 | 0.77 | MAPT (0.74) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3439640 | 0.77 | MAPT (0.62) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28916427 | 0.76 | KMT2A (0.79) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465724-B2 | Bis-pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates and a process for the preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-12-16 | — | — | US | disclosed |