SCHEMBL6901121

SCHEMBL6901121

COc1ccc(C)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.81
ALDH1A1 P00352 7/20 0.81
MEN1 O00255 5/20 0.81
KMT2A Q03164 5/20 0.81
KDM4E B2RXH2 4/20 0.81
TDP1 Q9NUW8 2/20 0.81
USP2 O75604 2/20 0.81
DUSP3 P51452 1/20 0.81
RAB9A P51151 7/20 0.72
SMN1; SMN2 Q16637 5/20 0.72
MAPK1 P28482 5/20 0.72
POLB P06746 3/20 0.72
NPSR1 Q6W5P4 3/20 0.72
ADORA2A P29274 2/20 0.72
FGB P02675 1/20 0.72
THRB P10828 1/20 0.72
PPARG P37231 1/20 0.72
NCOA2 Q15596 1/20 0.72
NCOA1 Q15788 1/20 0.72
NPC1 O15118 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Dimethoxyanthraquinone SCHEMBL3417221 0.90 MAPT (1.00) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL11690019 0.86 MAPT (0.59) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL9267831 0.84 ALDH1A1 (0.62) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL55743 0.84 ALDH1A1 (0.67) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL30886455 0.84 ALDH1A1 (0.67) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL2303569 0.84 MAPT (1.00) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL28916427 0.80 KMT2A (0.79) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL29494862 0.80 MAPT (0.79) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL9846513 0.80 MAPT (0.79) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL9846469 0.80 MAPT (0.79) MAPTALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6638356-B2 Gypsum as the main material and an anthraquinone compound incorporated. And suppresses, over a long period of time, generation of hydrogen sulfide by the action of sulfate-reducing bacteria, when it is landfilled as waste. KAWASAKI KASEI CHEMICALS LTD. (JP) 2003-10-28 US claimed
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-6638356-B2 Gypsum as the main material and an anthraquinone compound incorporated. And suppresses, over a long period of time, generation of hydrogen sulfide by the action of sulfate-reducing bacteria, when it is landfilled as waste. KAWASAKI KASEI CHEMICALS LTD. (JP) 2003-10-28 US disclosed
US-20030150363-A1 Incorporating an anthraquinone compound to which suppresses, over a long period of time, generation of hydrogen sulfide by the action of sulfate-reducing bacteria, when it is landfilled as waste. KAWASAKI KASEI CHEMICALS LTD. (JP) 2003-08-14 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed