Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 6/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401379 | 0.85 | MAPT (0.42) | PRKCIKDM4EMAPTRAD52MMP12 | |
| SCHEMBL11134 | 0.81 | PRKCI (0.53) | PRKCIKDM4EMAPTRAD52MMP12 | |
| SCHEMBL4756898 | 0.81 | PRKCI (0.53) | PRKCIKDM4EMAPTRAD52MMP12 | |
| Hydrochloric Acid SCHEMBL3671411 | 0.79 | KDM4E (0.55) | PRKCIKDM4EMAPTRAD52MMP12 | |
| SCHEMBL31546841 | 0.75 | MMP12 (0.47) | PRKCIKDM4EMAPTRAD52MMP12 | |
| SCHEMBL31546813 | 0.75 | MMP12 (0.47) | PRKCIKDM4EMAPTRAD52MMP12 | |
| SCHEMBL422512 | 0.74 | PRKCI (0.59) | PRKCIKDM4EMAPTRAD52MMP12 | |
| SCHEMBL11657970 | 0.73 | KDM4E (0.50) | PRKCIKDM4EMAPTRAD52MMP12 | |
| SCHEMBL8634290 | 0.73 | QPCT (0.68) | PRKCIKDM4EMAPTRAD52MMP12 | |
| SCHEMBL31619933 | 0.72 | PRKCI (0.57) | PRKCIKDM4EMAPTRAD52MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076285-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | DELPHIA THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| EP-1383761-B1 | Phenyl- and pyridyl-piperidines with tnf activity | SANOFI AVENTIS (FR) | 2011-03-02 | — | — | EP | disclosed |
| EP-1383762-B1 | TETRAHYDROPYRIDYL-ALKYL-HETEROCYCLES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-06-20 | — | — | EP | disclosed |
| EP-1383761-A1 | PHENYL- AND PYRIDYL-PIPERIDINES WITH TNF ACTIVITY | Sanofi-Aventis (FR) | 2004-01-28 | — | — | EP | disclosed |
| EP-1383762-A1 | TETRAHYDROPYRIDYL-ALKYL-HETEROCYCLES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sanofi-Aventis (FR) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002085887-A1 | PHENYL- AND PYRIDYL-PIPERIDINES WITH TNF ACTIVITY | SANOFI-SYNTHELABO (FR) | 2002-10-31 | — | — | WO | disclosed |
| WO-2002085888-A1 | TETRAHYDROPYRIDYL-ALKYL-HETEROCYCLES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-10-31 | — | — | WO | disclosed |