Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 8/20 | 0.68 |
| ▸ | QPCTL | Q9NXS2 | 5/20 | 0.68 |
| ▸ | PRKCI | P41743 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | RAD52 | P43351 | 1/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474515 | 0.92 | QPCT (0.60) | QPCTQPCTLPRKCIKDM4EMAPT | |
| SCHEMBL2462345 | 0.90 | QPCT (0.68) | QPCTQPCTLPRKCIKDM4EMAPT | |
| SCHEMBL7021141 | 0.88 | QPCT (0.66) | QPCTQPCTLPRKCIKDM4EMAPT | |
| SCHEMBL38665709 | 0.88 | QPCT (0.66) | QPCTQPCTLPRKCIKDM4EMAPT | |
| SCHEMBL22418756 | 0.87 | QPCT (0.64) | QPCTQPCTLPRKCIKDM4EMAPT | |
| SCHEMBL2457156 | 0.85 | QPCT (0.54) | QPCTQPCTLPRKCIKDM4EMAPT | |
| SCHEMBL23227763 | 0.84 | QPCT (0.60) | QPCTQPCTLPRKCIKDM4EMAPT | |
| SCHEMBL2461247 | 0.84 | QPCT (0.53) | QPCTQPCTLPRKCIKDM4EMAPT | |
| SCHEMBL484163 | 0.84 | QPCT (0.60) | QPCTQPCTLPRKCIKDM4EMAPT | |
| SCHEMBL2459101 | 0.84 | QPCT (0.54) | QPCTQPCTLPRKCIKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575968-A1 | COMPOUNDS FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASE | Summit Corporation Plc (GB) | 2013-04-10 | — | — | EP | claimed |
| WO-2011151621-A1 | COMPOUNDS FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASE | SUMMIT CORPORATION PLC (GB) | 2011-12-08 | — | — | WO | claimed |
| US-5824698-A | STAPHYLOCOCCUS, ENTEROCOCCUS OR HELIOBACTER | HOFFMAN-LA ROCHE INC. (US) | 1998-10-20 | — | — | US | disclosed |