Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952242 | 0.76 | ROCK2 (0.38) | TSHR | |
| SCHEMBL1888255 | 0.76 | CYP3A4 (0.33) | TSHR | |
| SCHEMBL7952241 | 0.76 | — | — | |
| SCHEMBL24406220 | 0.74 | EPHX1 (0.36) | — | |
| SCHEMBL1705197 | 0.73 | — | — | |
| SCHEMBL23024631 | 0.72 | TSHR (0.32) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL16899474 | 0.71 | — | — | |
| SCHEMBL15112813 | 0.70 | TSHR (0.35) | CTSLCTSBTSHR | |
| SCHEMBL19543440 | 0.69 | — | — | |
| SCHEMBL9818235 | 0.69 | BHMT (0.38) | CTSLCTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006776-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| EP-1670852-B1 | THERMOSETTING MATERIAL BASED ON ANTIPLASTICIZED POLYTHIOURETHANE, AND OPHTHALMIC LENS COMPRISING AN ANTIPLASTICIZED THERMOSETTING MATERIAL | ESSILOR INT (FR) | 2008-12-10 | — | — | EP | disclosed |