SCHEMBL14014456

SCHEMBL14014456

CC(N)c1cccc(Br)c1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.48
TDO2 P48775 1/20 0.48
MAOA P21397 1/20 0.47
ALDH1A1 P00352 2/20 0.44
MAPK1 P28482 1/20 0.44
MBTD1 Q05BQ5 1/20 0.41
L3MBTL3 Q96JM7 1/20 0.41
GBA1 P04062 1/20 0.40
ADRB1 P08588 1/20 0.38
MIF P14174 1/20 0.38
HTR2A P28223 1/20 0.38
ADRA1A P35348 1/20 0.38
HTR2B P41595 1/20 0.38
ADRB2 P07550 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
C1S P09871 1/20 0.38
PARP1 P09874 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL749481 1.00 IDO1 (0.48) IDO1TDO2MAOAALDH1A1MAPK1
SCHEMBL3689883 1.00 IDO1 (0.48) IDO1TDO2MAOAALDH1A1MAPK1
SCHEMBL842088 1.00 IDO1 (0.48) IDO1TDO2MAOAALDH1A1MAPK1
Hydrochloric Acid SCHEMBL4487718 0.98 IDO1 (0.52) IDO1TDO2MAOAALDH1A1MAPK1
Hydrochloric Acid SCHEMBL5214124 0.98 IDO1 (0.52) IDO1TDO2MAOAALDH1A1MAPK1
Hydrochloric Acid SCHEMBL4493494 0.98 IDO1 (0.52) IDO1TDO2MAOAALDH1A1MAPK1
SCHEMBL659099 0.83 ADRB2 (0.46) MAOAALDH1A1ADRB1MIFHTR2A
SCHEMBL29278100 0.83 IDO1 (0.46) IDO1TDO2MAOAALDH1A1MAPK1
SCHEMBL30762162 0.83 IDO1 (0.46) IDO1TDO2MAOAALDH1A1MAPK1
SCHEMBL2401036 0.83 IDO1 (0.46) IDO1TDO2MAOAALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894363-B Synthesis process of 6-bromo-1, 2,3, 4-tetrahydroisoquinoline 苏州艾缇克药物化学有限公司 2025-02-11 CN claimed
CN-116444598-B Ganoderic acid A derivative, its synthesis method and application in treating tumor 中国医学科学院药用植物研究所 2024-11-01 CN claimed
CN-115141197-B 3-aromatic heterocycle substituted phenyl derivative and preparation method and application thereof 安徽医科大学 2024-03-26 CN claimed
CN-116444598-A Ganoderic acid A derivative, its synthesis method and application in treating tumor 中国医学科学院药用植物研究所 2023-07-18 CN claimed
CN-115894363-A Synthesis process of 6-bromo-1,2,3,4-tetrahydroisoquinoline 苏州艾缇克药物化学有限公司 2023-04-04 CN claimed
CN-115141197-A 3-aromatic heterocyclic substituted phenyl derivative and preparation method and application thereof 安徽医科大学 2022-10-04 CN claimed
EP-4262788-B1 UREA OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME LLC (US) 2026-01-21 EP disclosed
EP-4598582-A1 PROTEOLYSIS-TARGETING CHIMERAS AGAINST THE PAPAIN-LIKE PROTEASE OF SARS-COV-2 Tocris Cookson Limited (GB) 2025-08-13 EP disclosed
CN-119954773-A PSMA compounds, pharmaceutical compositions comprising the same and uses thereof 苏州威智创科生物有限公司 2025-05-09 CN disclosed
CN-115894363-B Synthesis process of 6-bromo-1, 2,3, 4-tetrahydroisoquinoline 苏州艾缇克药物化学有限公司 2025-02-11 CN disclosed
CN-116589479-B Quinoxaline derivative with antifungal activity and application thereof 中国人民解放军海军军医大学 2024-11-22 CN disclosed
CN-116444598-B Ganoderic acid A derivative, its synthesis method and application in treating tumor 中国医学科学院药用植物研究所 2024-11-01 CN disclosed
CN-115677616-B Macrocyclic sulfonamide compound, preparation method and medical application thereof 中国药科大学 2024-10-18 CN disclosed
US-7456194-B2 Imidazo-fused oxazolo [4,5-b]pyridine and imidazo-fused thiazolo[4,5-b]pyridine based tricyclic compounds and pharmaceutical compositions comprising same BRISTOL-MYERS SQUIBB COMPANY (US) 2008-11-25 US disclosed
CN-100412062-C Synthesis of enantiomerically pure amino-substituted fused bicyclic rings ANORMED INC (CA) 2008-08-20 CN disclosed
CN-1272322-C Synthesis of enantiomerically pure amino-substituted fused bicyclic rings ANORMED INC (CA) 2006-08-30 CN disclosed
CN-1817864-A Synthesis of enantiomerically pure amino-substituted fused bicyclic rings ANORMED INC (CA) 2006-08-16 CN disclosed
CN-1608052-A Synthesis of enantiomerically pure amino-substituted fused bicyclic rings ANORMED INC (CA) 2005-04-20 CN disclosed
CN-1595677-A Solution deposition of chalcogenide films IBM (US) 2005-03-16 CN disclosed
CN-1577742-A Solution deposition of chalcogenide films IBM (US) 2005-02-09 CN disclosed