SCHEMBL3689883

SCHEMBL3689883

C[C@@H](N)c1cccc(Br)c1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.48
TDO2 P48775 1/20 0.48
MAOA P21397 1/20 0.47
ALDH1A1 P00352 2/20 0.44
MAPK1 P28482 1/20 0.44
MBTD1 Q05BQ5 1/20 0.41
L3MBTL3 Q96JM7 1/20 0.41
GBA1 P04062 1/20 0.40
ADRB1 P08588 1/20 0.38
MIF P14174 1/20 0.38
HTR2A P28223 1/20 0.38
ADRA1A P35348 1/20 0.38
HTR2B P41595 1/20 0.38
ADRB2 P07550 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
C1S P09871 1/20 0.38
PARP1 P09874 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL749481 1.00 IDO1 (0.48) IDO1TDO2MAOAALDH1A1MAPK1
SCHEMBL14014456 1.00 IDO1 (0.48) IDO1TDO2MAOAALDH1A1MAPK1
SCHEMBL842088 1.00 IDO1 (0.48) IDO1TDO2MAOAALDH1A1MAPK1
Hydrochloric Acid SCHEMBL4487718 0.98 IDO1 (0.52) IDO1TDO2MAOAALDH1A1MAPK1
Hydrochloric Acid SCHEMBL5214124 0.98 IDO1 (0.52) IDO1TDO2MAOAALDH1A1MAPK1
Hydrochloric Acid SCHEMBL4493494 0.98 IDO1 (0.52) IDO1TDO2MAOAALDH1A1MAPK1
SCHEMBL659099 0.83 ADRB2 (0.46) MAOAALDH1A1ADRB1MIFHTR2A
SCHEMBL29278100 0.83 IDO1 (0.46) IDO1TDO2MAOAALDH1A1MAPK1
SCHEMBL30762162 0.83 IDO1 (0.46) IDO1TDO2MAOAALDH1A1MAPK1
SCHEMBL2401036 0.83 IDO1 (0.46) IDO1TDO2MAOAALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119923169-A Method for improving circularly polarized light detection performance of perovskite film through achiral cations 复旦大学 2025-05-02 CN claimed
CN-118946165-A Interface interaction spin-photon conversion body heterostructure and preparation method 武汉大学 2024-11-12 CN claimed
CN-118922037-A Chiral photoelectric functional material with wide band gap and preparation method thereof 武汉大学 2024-11-08 CN claimed
CN-118745344-A Perovskite circular polarization luminescent material with chiral low-dimensional-three-dimensional heterojunction structure and application thereof 武汉大学 2024-10-08 CN claimed
EP-3490986-B1 PIPERIDINE CXCR7 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2021-11-24 EP claimed
US-10752620-B2 Piperdine CXCR7 receptor modulators IDORSIA PHARMACEUTICALS LTD. (CH) 2020-08-25 US claimed
US-20190169180-A1 PIPERDINE CXCR7 RECEPTOR MODULATORS ACTELION PHARMACEUTICALS LTD. (CH) 2019-06-06 US claimed
EP-3490986-A1 PIPERIDINE CXCR7 RECEPTOR MODULATORS Idorsia Pharmaceuticals Ltd (CH) 2019-06-05 EP claimed
WO-2018019929-A1 PIPERIDINE CXCR7 RECEPTOR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2018-02-01 WO claimed
EP-2763990-B1 PYRROLOPYRAZINE KINASE INHIBITORS HOFFMANN LA ROCHE (CH) 2017-02-22 EP claimed
US-8658646-B2 Pyrrolopyrazine kinase inhibitors HOFFMANN-LAROCHE INC. (US) 2014-02-25 US claimed
US-8084630-B2 Process for the synthesis of ramelteon and its intermediates TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2011-12-27 US claimed
US-20090281176-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2009-11-12 US claimed
EP-2098519-A1 Process for the synthesis of ramelteon and its intermediates Teva Pharmaceutical Industries Ltd. (IL) 2009-09-09 EP claimed
US-20090069581-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2009-03-12 US claimed
US-20260092045-A1 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2026-04-02 US disclosed
US-12558341-B2 Oral complement factor D inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
US-20060235033-A1 Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of macrophage colony stimulating factor receptor KIRIN BEER KABUSHIKI KAISHA (JP) 2006-10-19 US disclosed
EP-1535910-A1 QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR KIRIN BEER KABUSHIKI KAISHA (JP) 2005-06-01 EP disclosed
US-20020061564-A1 Generating phenylalanine and leucine using mutant enzymatic polypeptide; generate mutant enzyme, aminate ketoacid, recover amino acids CODEXIS, INC. 2002-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281176-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES CYP2B6, UGT1A6, CYP2A6 IDO1 4021/4885TDO2 1947/4885MAOA 1359/4885
US-20260092045-A1 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS TFPI, F3, BTK IDO1 2077/4885TDO2 874/4885MAOA 614/4885
US-12558341-B2 Oral complement factor D inhibitors CFD, CFH, CFB IDO1 3985/4885TDO2 3915/4885MAOA 1416/4885
US-20190169180-A1 PIPERDINE CXCR7 RECEPTOR MODULATORS CXCR1, CXCR5, ACKR3 IDO1 2279/4885TDO2 4798/4885MAOA 4615/4885
US-20060235033-A1 Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of macrophage colony stimulating factor receptor CSF3R, CSF1R, MSR1 IDO1 1962/4885TDO2 4377/4885MAOA 3667/4885
US-20090069581-A1 PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES CYP2B6, UGT1A6, CYP2A6 IDO1 2791/4885TDO2 721/4885MAOA 925/4885
US-10752620-B2 Piperdine CXCR7 receptor modulators CXCR1, CXCR5, ACKR3 IDO1 2279/4885TDO2 4798/4885MAOA 4615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.