SCHEMBL1401522

SCHEMBL1401522

CNCC1(C)C=CC=C(C(=O)N(C)[C@H](Cc2ccc3ccccc3c2)C(=O)N(C)[C@H](Cc2ccccc2)C(=O)N2CCC[C@H]2CN(C)C)C1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 18/20 0.40
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1401182 0.81 TACR1 (0.44) TACR1
SCHEMBL1401075 0.79 TACR1 (0.47) TACR1MAPT
SCHEMBL1401118 0.77 TACR1 (0.45) TACR1
SCHEMBL13760032 0.74 TACR1 (0.42) TACR1
SCHEMBL868029 0.74 GHSR (0.53) TACR1
SCHEMBL868030 0.74 GHSR (0.53) TACR1
SCHEMBL1401222 0.73 TACR1 (0.44) TACR1
SCHEMBL1401209 0.71 GHSR (0.51) TACR1
SCHEMBL1401307 0.71 GHSR (0.51) TACR1
SCHEMBL1401212 0.71 GHSR (0.51) TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1100824-B1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK AS (DK) 2011-03-02 EP claimed