Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.42 |
| ▸ | GHSR | Q92847 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | YAP1 | P46937 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401193 | 1.00 | TACR1 (0.42) | TACR1GHSROPRD1BCHEYAP1 | |
| SCHEMBL1401195 | 1.00 | TACR1 (0.42) | TACR1GHSROPRD1BCHEYAP1 | |
| SCHEMBL1401157 | 0.91 | P2RX7 (0.41) | TACR1GHSROPRD1YAP1ADORA1 | |
| SCHEMBL1401233 | 0.90 | MAPK1 (0.42) | BCHEYAP1ADORA1 | |
| SCHEMBL1401232 | 0.90 | MAPK1 (0.42) | BCHEYAP1ADORA1 | |
| SCHEMBL1401118 | 0.86 | TACR1 (0.45) | TACR1 | |
| SCHEMBL1401165 | 0.85 | GHSR (0.50) | TACR1GHSR | |
| SCHEMBL1401168 | 0.85 | GHSR (0.50) | TACR1GHSR | |
| SCHEMBL1401167 | 0.85 | GHSR (0.50) | TACR1GHSR | |
| SCHEMBL1401110 | 0.84 | TACR1 (0.42) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100824-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2011-03-02 | — | — | EP | disclosed |