SCHEMBL14015293

SCHEMBL14015293

CCC(C)c1cccc2c(OC)cccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
IDO1 P14902 1/20 0.39
BCHE P06276 1/20 0.39
TYR P14679 1/20 0.39
ACHE P22303 1/20 0.39
HTR2C P28335 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 1/20 0.38
SLC6A4 P31645 1/20 0.38
EP300 Q09472 1/20 0.38
KAT8 Q9H7Z6 1/20 0.38
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
RECQL P46063 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14015296 0.83 TSHR (0.40) TSHRL3MBTL1KDM4EMEN1CYP1A2
SCHEMBL6679628 0.83 TSHR (0.57) TSHRIDO1ACHEL3MBTL1KDM4E
SCHEMBL19314294 0.83 TSHR (0.57) TSHRIDO1ACHEL3MBTL1KDM4E
SCHEMBL19355318 0.83 TSHR (0.57) TSHRIDO1ACHEL3MBTL1KDM4E
SCHEMBL29657286 0.83 TSHR (0.57) TSHRIDO1ACHEL3MBTL1KDM4E
SCHEMBL13778072 0.82 TSHR (0.44) TSHRBCHETYRACHEHDAC4
SCHEMBL10182868 0.81 TSHR (0.41) TSHRHTR2CL3MBTL1KDM4EMEN1
SCHEMBL15033908 0.81 L3MBTL1 (0.45) TSHRL3MBTL1KDM4EMEN1CYP1A2
SCHEMBL11998999 0.80 ALDH1A1 (0.39) TSHRBCHETYRACHEKDM4E
SCHEMBL10182614 0.79 TSHR (0.39) TSHRL3MBTL1KDM4ESLC6A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7432034-B2 Negative resist composition FUJIFILM CORPORATION (JP) 2008-10-07 US disclosed