Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16330324 | 0.93 | DNM1 (0.33) | DNM1ALDH1A1LMNAGAAKDM4E | |
| SCHEMBL10005311 | 0.91 | DNM1 (0.40) | DNM1ALDH1A1LMNAKMT2ASLC22A2 | |
| SCHEMBL13611251 | 0.90 | DNM1 (0.34) | DNM1KDM4AHIF1ATET2DOHH | |
| SCHEMBL13813061 | 0.88 | CYP2C9 (0.34) | DNM1LMNAKMT2ACYP2C19GAA | |
| SCHEMBL18713491 | 0.87 | CASP2 (0.42) | DNM1ALDH1A1LMNAKMT2ASLC22A2 | |
| SCHEMBL13084321 | 0.87 | DNM1 (0.41) | DNM1ALDH1A1LMNAKMT2ASLC22A2 | |
| SCHEMBL18713490 | 0.86 | GAA (0.41) | DNM1ALDH1A1LMNAKMT2ASLC22A2 | |
| SCHEMBL10099837 | 0.86 | GAA (0.42) | DNM1ALDH1A1LMNASLC22A2SLC22A1 | |
| SCHEMBL16329013 | 0.85 | PAOX (0.39) | DNM1ALDH1A1LMNAKMT2ASLC22A2 | |
| SCHEMBL18163346 | 0.84 | DNM1 (0.45) | DNM1ALDH1A1LMNAKMT2ASLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080267903-A1 | Cationic polyamines and dendrimeric polymers; anti-proliferative agents; for treatment of neoplasms and tumours, inflammatory disorders, autoimmune disorders, psoriasis, and atherosclerosis; gene therapy | UNIVERSITY COLLEGE LONDON (GB) | 2008-10-30 | — | — | US | disclosed |
| US-20080267903-A1 | Cationic polyamines and dendrimeric polymers; anti-proliferative agents; for treatment of neoplasms and tumours, inflammatory disorders, autoimmune disorders, psoriasis, and atherosclerosis; gene therapy | UNIVERSITY COLLEGE LONDON (GB) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267903-A1 | Cationic polyamines and dendrimeric polymers; anti-proliferative agents; for treatment of neoplasms and tumours, inflammatory disorders, autoimmune disorders, psoriasis, and atherosclerosis; gene therapy | PCNA, SSB, PKD1 | DNM1 439/4885ALDH1A1 3983/4885LMNA 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.