SCHEMBL14015372

SCHEMBL14015372

O=S(=O)(O)OCc1c[nH]c2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.55
MEN1 O00255 6/20 0.53
KMT2A Q03164 6/20 0.53
MAPT P10636 5/20 0.53
CYP3A4 P08684 3/20 0.53
AHR P35869 1/20 0.53
GPR84 Q9NQS5 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.51
ALDH1A1 P00352 3/20 0.51
LMNA P02545 2/20 0.51
KDM4E B2RXH2 4/20 0.50
HPGD P15428 1/20 0.50
PKM P14618 1/20 0.49
SLC6A2 P23975 1/20 0.48
FNTA P49354 1/20 0.48
FNTB P49356 1/20 0.48
MPO P05164 2/20 0.47
CYP2D6 P10635 2/20 0.47
CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1177062 0.84 MEN1 (0.53) MEN1KMT2AMAPTCYP3A4AHR
SCHEMBL26996544 0.79 HTR2A (0.58) SLC22A6MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL26996481 0.79 HTR2A (0.58) SLC22A6MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL6054655 0.78 MEN1 (0.58) SLC22A6MEN1KMT2AMAPTCYP3A4
SCHEMBL13915153 0.78 MEN1 (0.62) MEN1KMT2AMAPTCYP3A4AHR
SCHEMBL3227189 0.77 LMNA (0.60) SLC22A6MEN1KMT2AMAPTCYP3A4
SCHEMBL10689820 0.77 MAPT (0.63) MEN1KMT2AMAPTCYP3A4AHR
SCHEMBL26936014 0.77 MAPT (0.55) MEN1KMT2AMAPTCYP3A4AHR
SCHEMBL30952641 0.75 HTR2A (0.57) MEN1KMT2AMAPTCYP3A4AHR
SCHEMBL28092238 0.75 SLC22A6 (0.49) SLC22A6MEN1KMT2AMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7442485-B2 Lithographic process involving on press development FUJIFILM CORPORATION (JP) 2008-10-28 US disclosed