Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | MPO | P05164 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | HTR1B | P28222 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867782 | 0.89 | SLC6A4 (0.54) | HTR2ACYP3A4CYP1A2HTR2CMPO | |
| SCHEMBL3867784 | 0.89 | SLC6A4 (0.54) | HTR2ACYP3A4CYP1A2HTR2CMPO | |
| SCHEMBL5513169 | 0.85 | HTR2A (0.64) | HTR2ACYP3A4CYP1A2HTR2CMPO | |
| SCHEMBL1272559 | 0.83 | HTR2A (0.57) | HTR2ACYP3A4CYP1A2HTR2CMPO | |
| SCHEMBL1272556 | 0.83 | HTR2A (0.57) | HTR2ACYP3A4CYP1A2HTR2CMPO | |
| Indolylpropionic Acid SCHEMBL15880225 | 0.83 | MAPT (0.54) | CYP3A4CYP1A2CYP2D6MAPTMEN1 | |
| SCHEMBL917538 | 0.83 | MC5R (0.59) | HTR2ACYP1A2CYP19A1MEN1KMT2A | |
| SCHEMBL6054655 | 0.83 | MEN1 (0.58) | HTR2ACYP3A4CYP1A2HTR2CMPO | |
| Tryptamine SCHEMBL27538374 | 0.82 | HTR2C (0.81) | HTR2ACYP3A4CYP1A2HTR2CMPO | |
| SCHEMBL28918284 | 0.82 | CYP19A1 (0.54) | HTR2ACYP1A2CYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140687-A1 | S1PR2 REGULATOR AND USE THEREOF | 北京昌平实验室 | 2024-07-04 | — | — | WO | disclosed |
| CN-118255830-A | S1PR2 modulators and uses thereof | 北京昌平实验室 | 2024-06-28 | — | — | CN | disclosed |