SCHEMBL14016100

SCHEMBL14016100

CNC1=NN(C)C(=O)/C1=C/C=C1\N(C)C(C)=C(C)C1(C)C

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.35
▸ MAPT P10636 3/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ LMNA P02545 2/20 0.35
▸ GAA P10253 2/20 0.35
▸ MAPK1 P28482 2/20 0.35
▸ HTT P42858 2/20 0.35
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13683591 0.80 L3MBTL1 (0.37) MEN1MAPTKMT2ALMNAGAA
SCHEMBL14610263 0.57 MAPT (0.50) MEN1MAPTKMT2ALMNAGAA
SCHEMBL13683597 0.56 MEN1 (0.30) MEN1MAPTKMT2ALMNAGAA
SCHEMBL13683641 0.54 RECQL (0.55) L3MBTL1
SCHEMBL10013323 0.54 — —
SCHEMBL14016516 0.53 — —
SCHEMBL14016145 0.53 — —
SCHEMBL14267879 0.52 MAPT (0.35) MEN1MAPTKMT2ALMNAGAA
SCHEMBL13270867 0.52 CTSD (0.30) LMNA
SCHEMBL13974402 0.50 RECQL (0.33) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1619040-B1 Thermal transfer recording material and thermal transfer recording method DAINIPPON PRINTING CO LTD (JP) 2008-11-19 — — EP disclosed
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