Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19735156 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1PRKCAAR | |
| SCHEMBL11001848 | 0.88 | TDP1 (0.50) | ALDH1A1TSHRTDP1PRKCAAR | |
| SCHEMBL8127701 | 0.87 | PRKCA (0.47) | ALDH1A1TDP1PRKCAARADRA1D | |
| Triacetin SCHEMBL3870 | 0.85 | TDP1 (0.56) | ALDH1A1TSHRTDP1PRKCAAR | |
| Triacetin SCHEMBL821340 | 0.85 | TDP1 (0.56) | ALDH1A1TSHRTDP1PRKCAAR | |
| SCHEMBL13449715 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TDP1PRKCAARADRA1D | |
| Triacetin SCHEMBL31301065 | 0.83 | TDP1 (0.54) | ALDH1A1TSHRTDP1PRKCAAR | |
| Triacetin SCHEMBL16446056 | 0.83 | TDP1 (0.54) | ALDH1A1TSHRTDP1PRKCAAR | |
| Triacetin SCHEMBL31035933 | 0.83 | TDP1 (0.54) | ALDH1A1TSHRTDP1PRKCAAR | |
| Triacetin SCHEMBL4367394 | 0.83 | TDP1 (0.54) | ALDH1A1TSHRTDP1PRKCAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305284-B1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PYRROLIDINES | UNIV MICHIGAN STATE (US) | 2008-11-12 | — | — | EP | disclosed |