Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156019 | 0.78 | MAPT (0.52) | LMNAKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL5903956 | 0.77 | KDM4E (0.51) | LMNAKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL11067956 | 0.74 | MAPT (0.46) | LMNAKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL14340900 | 0.74 | SLC2A1 (0.40) | LMNAKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL6510195 | 0.73 | MAPT (0.54) | LMNAKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL8974165 | 0.73 | NPC1 (0.53) | LMNAKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL5903966 | 0.73 | CYP2C19 (0.49) | LMNAKMT2AMEN1NPSR1NPC1 | |
| SCHEMBL27617094 | 0.72 | RAB9A (0.56) | LMNAKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL29392607 | 0.71 | KMT2A (0.50) | LMNAKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL3024397 | 0.71 | MAPT (0.53) | LMNAKMT2AALDH1A1MEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343503-B1 | HETEROARYL UREA NEUROPEPTIDE Y Y5 RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2008-11-12 | — | — | EP | disclosed |
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |