Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116229 | 1.00 | MAPT (0.53) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Methane SCHEMBL28159882 | 0.98 | MAPT (0.52) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL8872527 | 0.98 | ADRA2A (0.54) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Acetone SCHEMBL28243789 | 0.91 | CYP1A2 (0.57) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Phosphoric Acid SCHEMBL8529442 | 0.91 | ADRA2A (0.50) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Phosphoric Acid SCHEMBL9079479 | 0.88 | ADRA2A (0.47) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Cadaverine Tartrate SCHEMBL28586029 | 0.85 | ADRA2A (0.45) | MAPTLMNAADRA2AADRA2BADRA2C | |
| Cadaverine Tartrate SCHEMBL28598769 | 0.85 | ADRA2A (0.45) | MAPTLMNAADRA2AADRA2BADRA2C | |
| SCHEMBL19461607 | 0.84 | MAPT (0.71) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL25336501 | 0.83 | IDO1 (0.42) | MAPTLMNAADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060135589-A1 | 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors | ASTEX TECHNOLOGY, INC. (GB) | 2006-06-22 | — | — | US | claimed |
| JP-2006500348-A | — | — | 2006-01-05 | — | — | JP | claimed |
| EP-1534685-A1 | 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS CYCLIN DEPENDENT KINASES (CDK) INHIBITORS | Astex Technology Limited (GB) | 2005-06-01 | — | — | EP | claimed |
| WO-2004014864-A1 | 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS CYCLIN DEPENDENT KINASES (CDK) INHIBITORS | ASTEX TECHNOLOGY LIMITED (GB) | 2004-02-19 | — | — | WO | claimed |
| EP-0570250-B1 | Crystalline structure of monohydrogentartrates, process for its preparation and application thereof | FRANCE TELECOM (FR) | 1998-06-03 | — | — | EP | claimed |
| EP-0619308-B1 | Crystalline structures of halides of 2-amino-5-nitro-pyridinium, process for their preparation and an electrooptical device with such structures | FRANCE TELECOM (FR) | 1998-03-11 | — | — | EP | claimed |
| EP-0488869-B1 | Salts of 2-amino-5-nitropyridinium for non-linear and electro-optic use, and a process for their preparation | FRANCE TELECOM (FR) | 1996-02-07 | — | — | EP | claimed |
| US-5397508-A | 2-amino-5-nitropyridinium salts usable in non-linear optics and in electroptics and a process for preparing the same | FRANCE TELECOM ETABLISSEMENT AUTONOME DE DROIT PUBLIC (CENTRE NATIONAL D'ETUDES DES TELECOMMUNICATIONS) (FR) | 1995-03-14 | — | — | US | claimed |
| US-5374734-A | Monohydrogentartrate crystalline structure having nonlinear quadratic effects | FRANCE TELECOM (FR) | 1994-12-20 | — | — | US | claimed |
| EP-0619308-A1 | Crystalline structures of the hydrogen chloride salt of 2-amino-5-nitro-pyridinium, process for their preparation and an electrooptical device with such structures | FRANCE TELECOM (FR) | 1994-10-12 | — | — | EP | claimed |
| EP-0570250-A2 | Crystalline structure of monohydrogentartrates, process for its preparation and application thereof | FRANCE TELECOM (FR) | 1993-11-18 | — | — | EP | claimed |
| EP-0488869-A1 | Salts of 2-amino-5-nitropyridinium for non-linear and electro-optic use, and a process for their preparation | FRANCE TELECOM (FR) | 1992-06-03 | — | — | EP | claimed |
| JP-6080500-A | — | — | None | — | — | JP | disclosed |
| JP-5125049-A | — | — | None | — | — | JP | disclosed |
| US-20240068988-A1 | SYSTEMS AND METHODS FOR RAPID PATHOGEN DETECTION | MARSHALL DARRELL D (US) | 2024-02-29 | — | — | US | disclosed |
| WO-2022203601-A1 | COMPOUNDS USEFUL AS HAIR DYES | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2022-09-29 | — | — | WO | disclosed |
| JP-H05125049-A | NOVEL SALT OF 2AMINO-5NITROPYRYDINIUM USABLE IN NON-LINEAR OPTICS AND ELECTROOPTICS AND ITS PRODUCTION | CENTRE NATL ETUD TELECOMMUN (PTT) | 1993-05-21 | — | — | JP | disclosed |
| EP-0488869-A1 | Salts of 2-amino-5-nitropyridinium for non-linear and electro-optic use, and a process for their preparation | FRANCE TELECOM (FR) | 1992-06-03 | — | — | EP | disclosed |
| EP-0488869-A1 | Salts of 2-amino-5-nitropyridinium for non-linear and electro-optic use, and a process for their preparation | FRANCE TELECOM (FR) | 1992-06-03 | — | — | EP | disclosed |
| EP-0488869-A1 | Salts of 2-amino-5-nitropyridinium for non-linear and electro-optic use, and a process for their preparation | FRANCE TELECOM (FR) | 1992-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135589-A1 | 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors | CCNC, CDK1, CDK7 | MAPT 4723/4885LMNA 1489/4885ADRA2A 4096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.