Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14792478 | 0.84 | RECQL (0.37) | POLBBLMRECQLPKMMAPT | |
| SCHEMBL24848866 | 0.81 | BLM (0.41) | POLBBLMRECQLPKMMAPT | |
| SCHEMBL17548813 | 0.79 | MAOB (0.39) | POLBBLMRECQLPKMMAPT | |
| SCHEMBL16407768 | 0.73 | RECQL (0.38) | POLBBLMRECQLPKMMAPT | |
| SCHEMBL14018548 | 0.73 | CES2 (0.34) | — | |
| SCHEMBL14275417 | 0.72 | AKT1 (0.37) | RECQLMAPTCYP2C19CYP3A4TSHR | |
| SCHEMBL20365747 | 0.72 | AKT1 (0.37) | RECQLMAPTCYP2C19CYP3A4TSHR | |
| SCHEMBL13283403 | 0.72 | AKT1 (0.38) | POLBBLMRECQLPKMMAPT | |
| SCHEMBL2396375 | 0.71 | BLM (0.48) | POLBBLMRECQLPKMMAPT | |
| SCHEMBL3471389 | 0.71 | BLM (0.48) | POLBBLMRECQLPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343503-B1 | HETEROARYL UREA NEUROPEPTIDE Y Y5 RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2008-11-12 | — | — | EP | disclosed |