Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 13/20 | 0.58 |
| ▸ | UBE2M | P61081 | 2/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14018580 | 0.95 | NPY5R (0.62) | NPY5REPHX2CCR5USP30 | |
| SCHEMBL14018547 | 0.89 | UBE2M (0.49) | NPY5RUBE2MDCUN1D1EPHX2LMNA | |
| SCHEMBL14332117 | 0.89 | NPY5R (0.52) | NPY5RUBE2MDCUN1D1EPHX2LMNA | |
| SCHEMBL14332748 | 0.88 | NPY5R (0.60) | NPY5RUBE2MDCUN1D1EPHX2LMNA | |
| SCHEMBL14019243 | 0.88 | NPY5R (0.75) | NPY5RCCR5USP30 | |
| SCHEMBL14333150 | 0.88 | NPY5R (0.63) | NPY5RCCR5USP30 | |
| SCHEMBL14332254 | 0.87 | NPY5R (0.62) | NPY5REPHX2CCR5USP30 | |
| SCHEMBL14332287 | 0.86 | NPY5R (0.56) | NPY5RUBE2MDCUN1D1EPHX2LMNA | |
| SCHEMBL14332251 | 0.86 | NPY5R (0.60) | NPY5REPHX2CCR5USP30 | |
| SCHEMBL14332178 | 0.84 | NPY5R (0.55) | NPY5RUBE2MDCUN1D1EPHX2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343503-B1 | HETEROARYL UREA NEUROPEPTIDE Y Y5 RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2008-11-12 | — | — | EP | disclosed |
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |