Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.55 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14332235 | 0.93 | NPY5R (0.54) | NPY5RCCR5USP30EPHX2WNT3A | |
| SCHEMBL14018482 | 0.88 | NPY5R (0.50) | NPY5RCCR5USP30WNT3A | |
| SCHEMBL14332256 | 0.88 | NPY5R (0.50) | NPY5RCCR5USP30EPHX2WNT3A | |
| SCHEMBL14019175 | 0.88 | NPY5R (0.50) | NPY5RCCR5UBE2MDCUN1D1USP30 | |
| SCHEMBL14018932 | 0.88 | NPY5R (0.58) | NPY5RCCR5UBE2MDCUN1D1USP30 | |
| SCHEMBL14018553 | 0.88 | NPY5R (0.55) | NPY5RCCR5USP30WNT3AMAP4K4 | |
| SCHEMBL14332292 | 0.87 | NPY5R (0.51) | NPY5RCCR5USP30WNT3AMAP4K4 | |
| SCHEMBL14332109 | 0.87 | NPY5R (0.54) | NPY5RCCR5USP30EPHX2GSK3B | |
| SCHEMBL14019166 | 0.87 | NPY5R (0.54) | NPY5RCCR5USP30GSK3BDYRK1A | |
| SCHEMBL14332326 | 0.86 | NPY5R (0.56) | NPY5RGSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |