Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | RAC1 | P63000 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019081 | 0.94 | MAPT (0.68) | MAPTNQO1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL14019097 | 0.92 | MAPT (0.57) | MAPTNQO1ESR1ESR2CYP11B1 | |
| SCHEMBL14981161 | 0.89 | MAPT (0.59) | MAPTNQO1ESR1ESR2CYP11B1 | |
| SCHEMBL14019139 | 0.88 | MAPT (0.53) | MAPTESR1ESR2CYP11B1CYP11B2 | |
| SCHEMBL14019096 | 0.88 | MAPT (0.59) | MAPTNQO1ESR1ESR2CYP11B1 | |
| SCHEMBL14019090 | 0.87 | MAPT (0.58) | MAPTNQO1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL14019098 | 0.86 | MAPT (0.57) | MAPTNQO1ESR1ESR2CYP11B1 | |
| SCHEMBL5979409 | 0.85 | MAPT (0.51) | MAPTESR1ESR2CYP11B1CYP11B2 | |
| SCHEMBL14019083 | 0.83 | MAPT (0.62) | MAPTNQO1ESR1ESR2CYP11B1 | |
| SCHEMBL29690873 | 0.83 | ESR1 (0.55) | ESR1ESR2CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442447-B2 | Binaphthol based chromophores for the fabrication of blue organic light emitting diodes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442447-B2 | Binaphthol based chromophores for the fabrication of blue organic light emitting diodes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-28 | — | — | US | disclosed |