Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.48 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GUSB | P08236 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019134 | 0.94 | MAPT (0.56) | MAPTHPGDKDM4EALDH1A1LMNA | |
| SCHEMBL14019097 | 0.90 | MAPT (0.57) | MAPTHPGDKDM4EALDH1A1LMNA | |
| SCHEMBL14019086 | 0.88 | MAPT (0.64) | MAPTALDH1A1ESR1ESR2SMN1; SMN2 | |
| SCHEMBL14981161 | 0.87 | MAPT (0.59) | MAPTHPGDKDM4EALDH1A1ESR1 | |
| SCHEMBL14019096 | 0.85 | MAPT (0.59) | MAPTHPGDKDM4EALDH1A1LMNA | |
| SCHEMBL14019098 | 0.84 | MAPT (0.57) | MAPTHPGDKDM4EALDH1A1LMNA | |
| SCHEMBL5979409 | 0.83 | MAPT (0.51) | MAPTHPGDKDM4EALDH1A1LMNA | |
| SCHEMBL14019081 | 0.82 | MAPT (0.68) | MAPTKDM4EALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14019108 | 0.81 | KDM4E (0.64) | MAPTHPGDKDM4EALDH1A1LMNA | |
| SCHEMBL14019147 | 0.81 | MAPT (0.54) | MAPTHPGDKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442447-B2 | Binaphthol based chromophores for the fabrication of blue organic light emitting diodes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442447-B2 | Binaphthol based chromophores for the fabrication of blue organic light emitting diodes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-28 | — | — | US | disclosed |