Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 2/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019098 | 0.98 | MAPT (0.57) | MAPTNQO1ESR1ESR2CYP11B1 | |
| SCHEMBL14019097 | 0.95 | MAPT (0.57) | MAPTNQO1ESR1ESR2CYP11B1 | |
| SCHEMBL14019081 | 0.90 | MAPT (0.68) | MAPTNQO1CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL14981161 | 0.89 | MAPT (0.59) | MAPTNQO1ESR1ESR2CYP11B1 | |
| SCHEMBL14019134 | 0.88 | MAPT (0.56) | MAPTESR1ESR2ACACAHPGD | |
| SCHEMBL14019086 | 0.88 | MAPT (0.64) | MAPTNQO1ESR1ESR2CYP11B1 | |
| SCHEMBL14019139 | 0.85 | MAPT (0.53) | MAPTESR1ESR2CYP11B1CYP11B2 | |
| SCHEMBL5979409 | 0.85 | MAPT (0.51) | MAPTESR1ESR2CYP11B1CYP11B2 | |
| SCHEMBL25666349 | 0.83 | MAPT (0.56) | MAPTNQO1CYP11B1CYP11B2IDO1 | |
| SCHEMBL13015667 | 0.82 | CYP11B2 (0.58) | MAPTCYP11B1CYP11B2CYP19A1ACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442447-B2 | Binaphthol based chromophores for the fabrication of blue organic light emitting diodes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442447-B2 | Binaphthol based chromophores for the fabrication of blue organic light emitting diodes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-10-28 | — | — | US | disclosed |