Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14019254 | 0.93 | NPY5R (0.48) | NPY5RACKR3CCR5USP30EPHX2 | |
| SCHEMBL14332178 | 0.88 | NPY5R (0.55) | NPY5RACKR3CCR5UBE2MDCUN1D1 | |
| SCHEMBL14332398 | 0.88 | KIF11 (0.48) | NPY5RCCR5USP30KIF11 | |
| SCHEMBL14018587 | 0.87 | USP30 (0.44) | NPY5RCCR5USP30EPHX2CYP11B2 | |
| SCHEMBL14332258 | 0.85 | NPY5R (0.52) | NPY5RCCR5USP30EPHX2TP53 | |
| SCHEMBL14332397 | 0.85 | NPY5R (0.48) | NPY5RCCR5USP30EPHX2KIF11 | |
| SCHEMBL14019187 | 0.85 | NPY5R (0.51) | NPY5RACKR3USP30GSK3BDYRK1A | |
| SCHEMBL14332117 | 0.84 | NPY5R (0.52) | NPY5RCCR5UBE2MDCUN1D1USP30 | |
| SCHEMBL14332274 | 0.83 | USP30 (0.52) | USP30TP53 | |
| SCHEMBL14332314 | 0.83 | NPY5R (0.62) | NPY5RCCR5USP30TP53CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343503-B1 | HETEROARYL UREA NEUROPEPTIDE Y Y5 RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2008-11-12 | — | — | EP | disclosed |
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |