SCHEMBL140192

SCHEMBL140192

Nc1ccc(N)c(-c2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
HSD17B10 Q99714 3/20 0.58
CYP3A4 P08684 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAOA P21397 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
PTGDR2 Q9Y5Y4 1/20 0.47
NPC1 O15118 3/20 0.45
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
TP53 P04637 1/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
KMT2A Q03164 3/20 0.44
ATM Q13315 1/20 0.44
TLR9 Q9NR96 1/20 0.44
PTPRC P08575 2/20 0.43
NCOA1 Q15788 2/20 0.43
MEN1 O00255 2/20 0.43
HPGD P15428 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29460321 1.00 ALDH1A1 (0.58) ALDH1A1HSD17B10CYP3A4TDP1MAOA
Bromide SCHEMBL28748090 0.98 ALDH1A1 (0.56) ALDH1A1HSD17B10CYP3A4TDP1MAOA
Hydrochloric Acid SCHEMBL7870960 0.98 ALDH1A1 (0.56) ALDH1A1HSD17B10CYP3A4TDP1MAOA
Hydrochloric Acid SCHEMBL6570785 0.98 ALDH1A1 (0.56) ALDH1A1HSD17B10CYP3A4TDP1MAOA
SCHEMBL27745845 0.89 ALDH1A1 (0.58) ALDH1A1HSD17B10CYP3A4TDP1MAOA
Acetic Acid SCHEMBL7529999 0.88 PTGDR2 (0.51) ALDH1A1HSD17B10CYP3A4TDP1MAOA
Pyrimidine SCHEMBL27852568 0.87 ALDH1A1 (0.45) ALDH1A1HSD17B10CYP3A4TDP1MAOA
SCHEMBL22345011 0.86 MAOA (0.44) ALDH1A1HSD17B10CYP3A4TDP1MAOA
SCHEMBL30075769 0.85 TDP1 (0.50) ALDH1A1HSD17B10CYP3A4TDP1TAAR1
SCHEMBL2479814 0.85 TDP1 (0.50) ALDH1A1HSD17B10CYP3A4TDP1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2797 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080406-A High-temperature-resistant and thermally-dimensionally-stable soluble polyimide resin and preparation method and application thereof 2026-05-26 CN claimed
EP-4719411-A2 QUINOLINEAMINE AND PYRIDOQUINOLINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF Flexsys IP Holdings, LLC (US) 2026-04-08 EP claimed
EP-4687882-A2 6-AMINOQUINOLINE ANTIDEGRADANTS Flexsys IP Holdings, LLC (US) 2026-02-11 EP claimed
EP-4687881-A2 HETEROARYL ANTIDEGRADANTS Flexsys IP Holdings, LLC (US) 2026-02-11 EP claimed
EP-4676471-A2 QUINOLINEIMINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF Flexsys IP Holdings, LLC (US) 2026-01-14 EP claimed
CN-120136711-A Post-treatment method for product mixture for producing methyl isoamyl ketone 圣奥化学科技有限公司 2025-06-13 CN claimed
CN-119931172-A Rubber composition, green tire tread, tire and preparation method 山东丰源轮胎制造股份有限公司 2025-05-06 CN claimed
WO-2024249718-A2 QUINOLINEAMINE AND PYRIDOQUINOLINE ANTIDEGRADANT COMPOUNDS AND USES THEREOF FLEXSYS AMERICA L.P. (US) 2024-12-05 WO claimed
CN-118871411-A Process for cleaning a distillation unit of vinylaromatic compounds and process comprising such a cleaning process 道达尔能源一技术 2024-10-29 CN claimed
WO-2024206789-A2 6-AMINOQUINOLINE ANTIDEGRADANTS FLEXSYS AMERICA L.P. (US) 2024-10-03 WO claimed
EP-0567207-A2 Method of reducing impurities in aqueous monomer solutions ROHM AND HAAS COMPANY (US) 1993-10-27 EP claimed
EP-0326394-B1 IMPROVED RUBBER COMPOUND FOR TRACKED VEHICLE TRACK PADS US ARMY (US) 1993-05-05 EP claimed
WO-1993000066-A1 META-AMINOPHENOLS, THEIR USE AS COUPLERS FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYE COMPOSITIONS AND METHOD L'OREAL (FR) 1993-01-07 WO claimed
WO-1992017157-A1 NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS L'OREAL (FR) 1992-10-15 WO claimed
EP-0397343-A1 Blowing Agents SCHERING INDUSTRIAL PRODUCTS LIMITED (GB) 1990-11-14 EP claimed
EP-0338672-A1 Viscosity index improver, dispersant and anti-oxidant additive and lubricating oil composition containing same TEXACO DEVELOPMENT CORPORATION (US) 1989-10-25 EP claimed
WO-1989007121-A1 IMPROVED RUBBER COMPOUND FOR TRACKED VEHICLE TRACK PADS UNITED STATES OF AMERICA, REPRESENTED BY THE SECRE (US) 1989-08-10 WO claimed
EP-0326394-A1 Improved rubber compound for tracked vehicle track pads THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1989-08-02 EP claimed
US-4843114-A BLEND OF NITRILE RUBBER, FILLER, CURING AGENT AND ANTIDEGRADANT SYSTEM THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1989-06-27 US claimed
US-4089360-A SYNTHETIC AND NATURAL RUBBERS, SULFUR, AND SULFUR CURE ACCELERATORS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1978-05-16 US claimed