SCHEMBL1401923

SCHEMBL1401923

O=C1OCCOC(=O)c2c(O)ccc1c2O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 9/20 0.49
MAOB P27338 4/20 0.49
PSMB5 P28074 1/20 0.42
MAPT P10636 7/20 0.41
MEN1 O00255 7/20 0.41
KMT2A Q03164 7/20 0.41
ALDH1A1 P00352 6/20 0.41
TDP1 Q9NUW8 6/20 0.41
HPGD P15428 5/20 0.41
ALOX15 P16050 5/20 0.41
MAPK1 P28482 5/20 0.41
HSD17B10 Q99714 5/20 0.41
CYP3A4 P08684 4/20 0.41
THRB P10828 4/20 0.41
KDM4E B2RXH2 3/20 0.41
APEX1 P27695 3/20 0.41
RECQL P46063 3/20 0.41
USP2 O75604 3/20 0.41
TP53 P04637 2/20 0.41
BRCA1 P38398 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1401921 0.93 MAOA (0.46) MAOAMAOBPSMB5MAPTMEN1
SCHEMBL515083 0.91 MAOA (0.45) MAOAMAOBPSMB5MAPTMEN1
SCHEMBL12544787 0.86 MAPT (0.48) MAOAMAOBPSMB5MAPTMEN1
SCHEMBL31018377 0.83 PSMB5 (0.41) MAOAMAOBPSMB5MAPTMEN1
SCHEMBL1366417 0.83 PSMB5 (0.41) MAOAMAOBPSMB5MAPTMEN1
SCHEMBL12544323 0.79 MAOA (0.46) MAOAMAOBPSMB5MAPTMEN1
SCHEMBL541912 0.78 MAOA (0.44) MAOAMAOBPSMB5MAPTMEN1
SCHEMBL1401927 0.75 PSMB5 (0.38) MAOAMAOBPSMB5MAPTMEN1
SCHEMBL18860161 0.75 PSMB5 (0.38) MAOAMAOBPSMB5MAPTMEN1
SCHEMBL4438511 0.74 KCNJ1 (0.39) MAOAMAOBPSMB5MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586512-A Carbonate group-containing polyol, polyurethane resin composition, artificial coating film, and leather-like sheet 旭化成株式会社 2024-02-23 CN disclosed
EP-4321552-A1 CARBONATE GROUP-CONTAINING POLYOL, POLYURETHANE RESIN COMPOSITION, ARTIFICIAL LEATHER, AND LEATHER-LIKE SHEET Asahi Kasei Kabushiki Kaisha (JP) 2024-02-14 EP disclosed
EP-2639250-B1 URETHANE RESIN PARTICLES SANYO CHEMICAL IND LTD (JP) 2021-01-06 EP disclosed
US-10252377-B2 Aqueous aluminum brazing composition HARIMA CHEMICALS, INCORPORATED (JP) 2019-04-09 US disclosed
EP-2985112-B1 AQUEOUS COMPOSITION FOR ALUMINUM BRAZING HARIMA CHEMICALS INC (JP) 2018-08-22 EP disclosed
EP-2292676-B1 POLYURETHANE FOAM FOR FLAME-LAMINATING INOUE MTP KK (JP) 2017-04-19 EP disclosed
US-9550874-B2 Powdered polyurethane urea resin composition for slush molding and manufacturing process therefor SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2017-01-24 US disclosed
US-20160052092-A1 AQUEOUS ALUMINUM BRAZING COMPOSITION HARIMA CHEMICALS, INCORPORATED (JP) 2016-02-25 US disclosed
EP-2985112-A1 AQUEOUS COMPOSITION FOR ALUMINUM BRAZING Harima Chemicals, Inc. (JP) 2016-02-17 EP disclosed
US-9243103-B2 Polyurethane foam for flame-laminating INOAC CORPORATION (JP) 2016-01-26 US disclosed
US-9023941-B2 Urethane resin particles SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2015-05-05 US disclosed
US-20140179864-A1 POWDERED POLYURETHANE UREA RESIN COMPOSITION FOR SLUSH MOLDING AND MANUFACTURING PROCESS THEREFOR SANYO CHEMICAL INDUSTRIES, LTD (JP) 2014-06-26 US disclosed
EP-2740749-A1 POWDERED POLYURETHANE UREA RESIN COMPOSITION FOR SLUSH MOLDING AND MANUFACTURING PROCESS THEREFOR Sanyo Chemical Industries, Ltd. (JP) 2014-06-11 EP disclosed
EP-2639250-A1 URETHANE RESIN PARTICLES Sanyo Chemical Industries, Ltd. (JP) 2013-09-18 EP disclosed
US-20130237664-A1 URETHANE RESIN PARTICLES SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2013-09-12 US disclosed
US-20110091689-A1 POLYURETHANE FOAM FOR FLAME-LAMINATING INOAC CORPORATION (JP) 2011-04-21 US disclosed
EP-2292676-A1 POLYURETHANE FOAM FOR FLAME-LAMINATING Inoac Corporation (JP) 2011-03-09 EP disclosed
US-5281655-A Hydroxy- or carboxy-containing acrylic resins, alkyd resins, epoxy resins, fluorine-containing resins, urethane resins, crosslinking agent KANSAI PAINT COMPANY, LIMITED (JP) 1994-01-25 US disclosed
US-5227422-A Water soluble resin, polyurethane, crosslinking agent, clear coating, one-step baking KANSAI PAINT COMPANY, LIMITED (JP) 1993-07-13 US disclosed