Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 7/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31018377 | 0.85 | PSMB5 (0.41) | KCNJ1MAOAMAOBPSMB5KDM4E | |
| SCHEMBL1366417 | 0.85 | PSMB5 (0.41) | KCNJ1MAOAMAOBPSMB5KDM4E | |
| SCHEMBL18860161 | 0.77 | PSMB5 (0.38) | KCNJ1MAOAMAOBPSMB5KDM4E | |
| SCHEMBL1401927 | 0.77 | PSMB5 (0.38) | KCNJ1MAOAMAOBPSMB5KDM4E | |
| SCHEMBL1401912 | 0.75 | MAOA (0.39) | MAOAMAOBPSMB5ALDH1A1LMNA | |
| SCHEMBL1401923 | 0.74 | MAOA (0.49) | MAOAMAOBPSMB5KDRAURKB | |
| SCHEMBL12544787 | 0.72 | MAPT (0.48) | MAOAMAOBPSMB5AXLKDM4E | |
| SCHEMBL17504255 | 0.69 | PSMB5 (0.36) | KCNJ1MAOAMAOBPSMB5KDM4E | |
| SCHEMBL2452636 | 0.69 | MAOA (0.44) | MAOAMAOBKDM4EALDH1A1LMNA | |
| SCHEMBL1401921 | 0.68 | MAOA (0.46) | MAOAMAOBPSMB5KDRAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4294859-B2 | — | — | 2009-07-15 | — | — | JP | claimed |
| JP-2002514661-A | — | — | 2002-05-21 | — | — | JP | claimed |
| EP-1023369-A1 | DEPOLYMERIZATION PROCESS FOR RECYCLING POLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 2000-08-02 | — | — | EP | claimed |
| WO-1999020684-A1 | DEPOLYMERIZATION PROCESS FOR RECYCLING POLYESTERS | EASTMAN CHEMICAL COMPANY (US) | 1999-04-29 | — | — | WO | claimed |